Science Prediction Markets

Live Polymarket odds on scientific outcomes, discoveries and space missions.

Top Science markets on Polymarket by volume
Market	Volume
Will the US confirm that aliens exist by...?	$72.2M
Measles cases in U.S. in 2026?	$8.1M
Largest IPO by market cap in 2026?	$6.5M
Human moon landing in 2026?	$2.0M
New pandemic in 2026?	$1.2M
Will the Doge-1 Lunar Mission launch by...?	$1.1M
OpenAI announces another Millennium Prize solution by...?	$759K
FDA approves Retatrutide this year?	$594K
How many SpaceX Starship launches reach space in 2026?	$521K
Will CMI declare a Millennium Prize Problem solved by ___?	$434K
AI lab announces another Millennium Prize solution by...?	$411K
How many SpaceX launches in 2026?	$336K
Plague pandemic in 2026?	$281K
How many more Millennium Prize Problems will AI solve in 2026?	$250K
Which Millennium Prize Problem will AI solve next?	$242K
U.S. enacts AI safety bill before 2027?	$199K
Will Bitcoin replace SHA-256 before 2027?	$198K
FDA approves skin cancer vaccine by...?	$155K
SpaceX Starship fully reusable before 2027?	$123K
Anthropic announces a Millennium Prize solution by...?	$76K
Another pneumonic plague case in Russia by...?	$60K
Russia pneumonic plague spreads abroad?	$57K
Which math problems will AI solve in 2026?	$57K
Skin cancer vaccine BLA submitted by...?	$53K
Will CMI declare the Riemann Hypothesis solved by ___?	$33K

Updated 2026-10-08